Current research suggests that the presence of DNA damage in sperm can more than double the risk of miscarriage. This is very significant: until now, miscarriage has mostly been thought of as a female problem. In turn, research into the causes and prevention of miscarriage has focused on women and not on men. To understand the role of sperm damage in miscarriage, we need to find out how sperm get damaged in the first place. One way this could happen is if sperm come into contact with reactive oxygen species, which are very reactive chemicals that are made naturally by the body but can also come from outside sources such as smoking.
Most Americans think lost pregnancies are rare, according to surveys , but the reality is that up to 1 in 3 pregnancies will end in miscarriage, experts say. Experts including Jeve break down miscarriages into two categories. The risk for chromosomal abnormalities goes up as a woman ages. Richard Bronson, director of reproductive endocrinology at Stony Brook University. But there are probably multiple factors that, together, result in a lost pregnancy, he adds.
Around a quarter of all couples will experience a miscarriage. High levels of sperm DNA fragmentation have been shown to double the likelihood of a miscarriage occurring. Around a quarter of all couples will experience the heartache of miscarriage at some time.